Status:
COMPLETED
Budesonide for Emergency Treatment of Acute Wheezing in Children
Lead Sponsor:
Kecioren Education and Training Hospital
Conditions:
Asthma
Acute Asthma
Eligibility:
All Genders
6-6 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.
Detailed Description
Context: Inhaled steroids reduced admission rates in patients with acute asthma, but it is unclear if there is a benefit of inhaled corticosteroids when used in addition to systemic corticosteroids. T...
Eligibility Criteria
Inclusion
- Children who have recurrent wheezing attacks and admitted to the emergency room for acute wheezing
- Pulmonary index score of 7-13
- Parental/guardian permission (informed consent) and if appropriate, child assent
Exclusion
- Systemic corticosteroid use in the last 30 days
- Chronic lung diseases including cystic fibrosis
- Immunodeficiency
- Cardiac disease requiring surgery or medications
- Adverse drug reaction or allergy to budesonide, albuterol, ipratropium bromide, prednisone, prednisolone, or methylprednisolone
- Known renal or hepatic dysfunction
- Impending respiratory failure requiring positive pressure ventilation
- Immune deficiency
- Gastroesophageal reflux disease
- Suspected foreign body aspiration or croup
- Anatomic abnormalities of the respiratory tract
Key Trial Info
Start Date :
September 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00733317
Start Date
September 1 2007
End Date
December 1 2009
Last Update
December 20 2011
Active Locations (1)
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1
Kecioren Education and Training Hospital
Ankara, Kecioren, Turkey (Türkiye), 06380