Status:

UNKNOWN

The Use of Prostaglandin E1 in Head and Neck Microsurgery

Lead Sponsor:

National Taiwan University Hospital

Conditions:

Microsurgery

Head and Neck

Eligibility:

All Genders

20-80 years

Phase:

PHASE4

Brief Summary

Prostaglandin E1 (PGE1 )has been shown to have vasodilatation and anti-thrombosis effects, so it is used by some surgeons after microsurgery to keep the patency of the anastomosed small vessels. Howev...

Detailed Description

Despite meticulous microsurgical techniques, free flap failure due to postoperative vessel thrombosis cannot be completely eliminated. Postoperative pharmacological augmentation of the established blo...

Eligibility Criteria

Inclusion

  • Patients requiring microvascular reconstruction after head and neck cancer resection

Exclusion

  • Patients with coagulation dysfunction

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2010

Estimated Enrollment :

242 Patients enrolled

Trial Details

Trial ID

NCT00733434

Start Date

July 1 2008

End Date

July 1 2010

Last Update

October 27 2009

Active Locations (1)

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Page 1 of 1 (1 locations)

1

National taiwan University Hospital

Taipei, Taiwan, 100