Status:

COMPLETED

Outcome Study of Total Knee Arthroplasty in Asian Patients

Lead Sponsor:

DePuy International

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

Up to 75 years

Phase:

PHASE4

Brief Summary

To determine how the LCS mobile bearing knee system works within the Asian Population.

Detailed Description

The objective of this clinical evaluation is to compile a profile of the performance of the LCS Mobile bearing total knee system in normal clinical practice within the Asian Population. Performance wi...

Eligibility Criteria

Inclusion

  • Administrative - the patient is able to understand the evaluation, is able to give consent and will comply with the postoperative follow up regime.
  • Diagnosis - idiopathic osteoarthritis, rheumatoid arthritis, post traumatic arthritis or any other pathology that in the opinion of the clinical investigator requires a primary total knee arthroplasty.
  • Implant suitability - patients who in the opinion of the Clinical Investigator are considered suitable for treatment with a mobile bearing knee system (the LCS Classic or Universal).
  • Bilateral patients - simultaneous bilateral patients are included. Staged bilateral patients are included if the second procedure is performed within the one-year recruitment period. Staged bilateral patients where the second procedure is performed outside of the one-year recruitment period will only be included if the second procedure is performed within 6 months of the end of the one-year recruitment period.
  • Age - the upper age limit is set at 75 years and expected to live through the 5 years study period.vi. Ethnic Origin - patients must be Asian in ethnic origin
  • Unicondylar / High Tibial Osteotomy (HTO) conversion - patients that are being converted from a unicondylar / HTO procedure are included providing the reason for conversion is due to progression of the disease process affecting the other condyle. Patients that are converted and have evidence of infection / aseptic loosening / loss of bone stock are excluded.

Exclusion

  • Patients with a known history of poor compliance to medical treatment.
  • Patients that require revision surgery
  • Patients with gross ligamentous insufficiency.
  • Patients with a severe valgus deformity (15 degrees or greater)
  • Patients with a severe varus deformity (20 degrees or greater)
  • Patients with a fixed flexion contracture (30 degrees or greater)
  • Patients over the age of 75 years.

Key Trial Info

Start Date :

April 1 2000

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2008

Estimated Enrollment :

607 Patients enrolled

Trial Details

Trial ID

NCT00733694

Start Date

April 1 2000

End Date

April 1 2008

Last Update

February 28 2025

Active Locations (1)

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1

Department of Orthopaedic Surgery University of Hong Kong

Hong Kong, China