Status:

UNKNOWN

Early Detection of Atherosclerosis: a Randomized Trial in the Primary Prevention of Cardiovascular Diseases.

Lead Sponsor:

Hospital Arnau de Vilanova

Collaborating Sponsors:

Pfizer

Conditions:

Atherosclerosis

Cardiovascular Diseases

Eligibility:

All Genders

40-74 years

Phase:

PHASE4

Brief Summary

The incidence of cardiovascular diseases is still high and further efforts should be done in primary prevention. The main objective is to quantify the burden of subclinical atherosclerosis using non-i...

Detailed Description

We will perform non-invasive techniques (carotid Intima-Media Thickness, CAC score and ankle-brachial index) to individuals at intermediate cardiovascular risk.With these results, we will classify par...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • One or more of the following:
  • Familiar History of early-onset cardiovascular disease (male \< 55 or female \< 65).
  • Type 2 Diabetes mellitus or type 1 with microalbuminuria.
  • Essential High Blood Pressure.
  • Chronic Kidney Disease.
  • Primary hyperlipidemia.
  • The presence of two or more of the following:
  • Current smoker.
  • Physical inactivity.
  • High blood pressure (recently diagnosed).
  • Abdominal perimeter: \> 102 cm. males; \> 88 cm. females.
  • Total cholesterol \> 240 mg/dL.
  • HDL cholesterol ≤ 40 mg/dL males, ≤ 50 mg/dL females.
  • Exclusion Criteria:
  • Age \< 40 or \> 74 years old.
  • Previous Cardiovascular Event.

Exclusion

    Key Trial Info

    Start Date :

    April 1 2008

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    May 1 2013

    Estimated Enrollment :

    2948 Patients enrolled

    Trial Details

    Trial ID

    NCT00734123

    Start Date

    April 1 2008

    End Date

    May 1 2013

    Last Update

    August 14 2008

    Active Locations (1)

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    1

    Hospital Arnau de Vilanova

    Lleida, Catalonia, Spain, 25260