Status:

WITHDRAWN

Efficacy and Safety of a Cutaneous Formulation of Gonyautoxin 2/3 (GTX 2/3) for the Treatment of Facial Wrinkles

Lead Sponsor:

Phytotox SA

Conditions:

Facial Wrinkles

Eligibility:

FEMALE

30-60 years

Phase:

PHASE1

PHASE2

Brief Summary

The main objective of the trial is to determine whether the current topical formulation of GTX 2/3 reduces the wrinkling of the skin (crow's feet) after a single application Other evaluation criteria...

Detailed Description

This is a single volunteer group study. Each volunteer will be her own control. A volunteer will receive the active product containing cream on one side of her face and will receive the placebo cream ...

Eligibility Criteria

Inclusion

  • Women with no bearing-child potential or with adequate birth control method.
  • Volunteers between 30 to 60 years of age.
  • Subjects with bilateral crow's feet wrinkles.
  • Regular user of cosmetic products, willing and able to comply with the study objectives.
  • Signed informed consent.

Exclusion

  • Any medical condition or any use of a medication that could modify the study results (e.g.: NSAIDs, immunosuppressant drugs, insulin...).
  • Any other significant medical condition (e.g.: diabetes mellitus, heart disease, liver disease...).
  • Any other condition that in the investigator's opinion could not be appropriate with the participation in this trial.
  • Any health condition that could affect the evaluation of study parameters.
  • Acute or chronic skin disease.
  • History of allergic reaction to cosmetic compounds.
  • Pregnancy, planned pregnancy or breast-feeding.
  • Allergy to shellfish, fish or sea product (seaweed).
  • Known or suspected hypersensitivity to any of the study product compounds.
  • Participation in another clinical trial within 30 days previous to enrolment.
  • Known or suspected alcohol or drug abuse.

Key Trial Info

Start Date :

August 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2008

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00734786

Start Date

August 1 2008

End Date

September 1 2008

Last Update

August 25 2008

Active Locations (1)

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1

CLAIM

Buenos Aires, Buenos Aires F.D., Argentina