Status:
COMPLETED
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
University of Minnesota
Conditions:
Sepsis
Primary Myopathies
Eligibility:
All Genders
18+ years
Brief Summary
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e...
Detailed Description
A force measuring system similar to one employed in previous studies will be redesigned with a new stimulator system and leg support system. This new, small, light and portable measurement system accu...
Eligibility Criteria
Inclusion
- Any patient which fulfills the criteria for sepsis / septic shock according the definition of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference
- Patients who will be sedated, mechanically ventilated, and immobilized
- Patients will be intubated the day of admission to ICU and started mechanically ventilated on a positive pressure ventilation modus
- The severity of each patient¢s illness will be assessed using the Acute Physiology and Chronic Health Evaluation (APACHE) II score with required entry scores of a minimum of 15-20 Points
- Patients suffering from a primary myopathy, e.g., Duchenne Muscular Dystrophy or subclinic myopathy, e.g. Malignant Hyperthermia.
Exclusion
- Patients with neuropathies, consuming diseases in an advanced state (metastatic cancer) and severe infectious diseases (e.g. AIDS, Hepatitis), as well as patients with injured legs and/or patients requiring neuromuscular blocking drugs.
- Patients under the age of 18 yr.
Key Trial Info
Start Date :
September 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2019
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00735384
Start Date
September 1 2006
End Date
December 30 2019
Last Update
November 29 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Basel Hospital
Basel, Switzerland, CH-4031