Status:
COMPLETED
Executive, Activities of Daily Living, and Cholinergic Functions in Parkinson's Disease
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
Michael J. Fox Foundation for Parkinson's Research
Conditions:
Parkinson's Disease
Eligibility:
All Genders
50-85 years
Brief Summary
This research study will evaluate functions of memory, thinking, behavior, and daily life activities and how these relate to the measurement of certain chemicals (acetylcholine and dopamine) in the br...
Eligibility Criteria
Inclusion
- PDD: Patients who meet the UK Parkinson's Disease Society Brain Bank Research Center (UKPDSBRC) clinical diagnostic criteria for PD with dementia (MMSE 18-25; n=28; age 50-85 years; M/F) are eligible for the study. Hoehn and Yahr stages I-III.
- PD. Patients with who meet the UKPDSBRC criteria for PD with a MMSE of \>25 (n=28; age 50-85 years; M/F). Hoehn and Yahr stages I-III.
- Normal control subjects (n=16) (age 50-85 years; M/F).
- No current or past history of neurologic or psychiatric illness.
Exclusion
- Any subjects on cholinergic, anti-cholinergic drugs will be excluded from the study.
- Current or past history of neurologic or psychiatric illness.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2009
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT00737217
Start Date
March 1 2006
End Date
April 1 2009
Last Update
June 26 2013
Active Locations (1)
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1
University of Michigan Functional, Cognitive and Mobility Laboratory
Ann Arbor, Michigan, United States, 48106