Status:
COMPLETED
Cardiopulmonary Exercise Testing and Preoperative Risk Stratification
Lead Sponsor:
University College London Hospitals
Collaborating Sponsors:
University Hospital Southampton NHS Foundation Trust
Conditions:
Colorectal Cancer
Anaesthesia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The investigators would like to evaluate the use of cardiopulmonary exercise tests (CPX) in guiding the care pathway of patients undergoing colorectal operations. In the intervention group care will b...
Detailed Description
Each year 20000 UK patients die within 30 days of surgery. It seems that in the UK a patient's chances of becoming seriously unwell or dying following surgery is higher than in comparable countries. F...
Eligibility Criteria
Inclusion
- Adults ≥ 18 years age
- Males
- Females
- Listed for elective(non-emergency) colorectal surgery
Exclusion
- Age \< 18 years age
- Patient unwilling/unable to consent
- Adults with learning disabilities or dementia
- Prisoners
- Any contraindication to cardiopulmonary exercise testing (as outlined by \*American Association of Anaesthesia:
- Acute MI (3-5 days)
- Unstable angina
- Uncontrolled arrhythmias
- Syncope
- Acute endocarditis
- Acute myocarditis
- Acute pericarditis
- Symptomatic severe aortic stenosis
- Uncontrolled heart failure
- Acute pulmonary embolism or infarction
- Thrombosis of lower extremities
- Dissecting aneurysm
- Uncontrolled asthma
- Pulmonary oedema
- Room air desaturation at rest \<85%
- Respiratory failure
- Acute non-cardiopulmonary disorder that may affect exercise performance or be aggravated by exercise Mental impairment leading to inability to co-operate
- Patients already enrolled in an interventional study
- Previous CPX test result recorded in the medical notes
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
228 Patients enrolled
Trial Details
Trial ID
NCT00737828
Start Date
August 1 2008
End Date
May 1 2014
Last Update
May 21 2014
Active Locations (3)
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1
Whittington Hospital NHS Trust
London, United Kingdom, N19 5NF
2
University College London Hospitals NHS Foundation Trust
London, United Kingdom, NW1 2BU
3
Southampton University Hospitals NHS Trust
Southampton, United Kingdom