Status:
COMPLETED
Diagnostic Accuracy of Multi-Detector Spiral Computed Tomography Angiography Using 64 Detectors
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Toshiba America Medical Systems, Inc.
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
To compare the diagnostic ability of 64-detector MDCT coronary angiography with conventional invasive coronary angiography in patients with suspected coronary artery disease.
Detailed Description
The "Coronary Evaluation Using Multidetector Spiral Computed Tomography Angiography using 64 Detectors" or "CorE-64" study was designed to evaluate the diagnostic accuracy of multislice spiral CT angi...
Eligibility Criteria
Inclusion
- Male or female patients, age 40 years or greater.
- Women of child bearing potential must demonstrate a negative pregnancy test within 24 hours of the study MDCT.
- Suspected coronary artery disease (i.e. symptoms, signs) with a clinical indication for coronary angiography; and planned coronary angiography within the next 30 days.
- Able to understand and willing to sign informed consent.
Exclusion
- Known allergy to iodinated contrast media
- History of contrast-induced nephropathy
- History of multiple myeloma or previous organ transplantation
- Elevated serum creatinine (\> 1.5mg/dl) OR calculated creatinine clearance of \< 60 ml/min (using the Cockcroft-Gault formula
- Atrial fibrillation or uncontrolled tachyarrhythmia, or heart block
- Evidence of severe symptomatic heart failure; moderate or severe aortic stenosis
- Previous coronary artery bypass or other cardiac surgery
- Coronary artery intervention within the last 6 months
- Intolerance or contraindication to beta-blockers
- Body Mass Index \> 40.
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
405 Patients enrolled
Trial Details
Trial ID
NCT00738218
Start Date
October 1 2005
Last Update
August 20 2008
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.