Status:
COMPLETED
A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
Centre national de recherche et de formation sur le paludisme
Malaria Research and Training Centre, Mali
Conditions:
Malaria
Eligibility:
All Genders
3-59 years
Phase:
NA
Brief Summary
An investigation will be made of the combined impact of insecticide-treated nets and intermittent preventive treatment with amodiaquine + sulfadoxine-pyrimethamine on malaria morbidity in children in ...
Detailed Description
The trial will be conducted in 6000 children in Burkina Faso and Mali in 2008 and 2009. Each site will enroll 3,000 children. All children will be allocated a long lasting insecticide-treated net and ...
Eligibility Criteria
Inclusion
- Permanent residence in the study area with no intention of leaving during the surveillance period.
- Obtention of informed consent.
Exclusion
- Temporary residence in the study area.
- Absence of informed consent.
- Presence of a severe, chronic illness such as severe malnutrition (Kwashiorkor or marasmus) or AIDS, likely to interfere with evaluation of the trial results.
- A history of a previous, significant adverse reaction to either of the study drugs.
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
6000 Patients enrolled
Trial Details
Trial ID
NCT00738946
Start Date
August 1 2008
End Date
December 1 2009
Last Update
June 4 2010
Active Locations (2)
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1
Centre National de Recherche et de Formation sur le Paludisme
Ouagadougou, Kadiogo, Burkina Faso, BP 2208
2
Malaria Research and Training Centre
Bamako, Mali