Status:

COMPLETED

Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder

Lead Sponsor:

New York State Psychiatric Institute

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Post-Traumatic Stress Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.

Detailed Description

Post-traumatic stress disorder (PTSD) is caused by a traumatic experience often involving physical harm or the threat of harm or death. The emotional numbness and traumatic flashbacks symptomatic of P...

Eligibility Criteria

Inclusion

  • Meets DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) criteria for primary, chronic PTSD
  • At least moderately severe symptoms, defined by a minimum total (frequency plus severity) Clinician-Administered PTSD Scale score greater than 50
  • Willing to undergo an independent clinical assessment and other ratings

Exclusion

  • Diagnosis of schizophrenia, bipolar disorder, or other psychotic disorders
  • Psychiatric disorder due to a general medical condition
  • Current substance abuse or dependence
  • Acute suicide or homicide risk
  • Unstable or life-threatening medical condition
  • Primary diagnosis of borderline personality disorder, major depressive disorder, or major depression, melancholic subtype
  • Diagnosis of antisocial personality disorder
  • At least partial benefit from current treatment regimen
  • Unwillingness to discontinue current ineffective psycho- or pharmacotherapy
  • Inability to speak or read English

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2014

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT00739765

Start Date

April 1 2008

End Date

March 1 2014

Last Update

March 5 2019

Active Locations (1)

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New York State Psychiatric Institute

New York, New York, United States, 10032