Status:

UNKNOWN

A Phase II Study of AS1411 in Renal Cell Carcinoma

Lead Sponsor:

Antisoma Research

Conditions:

Metastatic Renal Cell Carcinoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The aim of this study is to evaluate the efficacy of AS1411 in patients with Metastatic Renal Cell Carcinoma

Eligibility Criteria

Inclusion

  • Histologically or cytologically confirmed renal cell carcinoma containing predominant clear cell histology
  • Failed or intolerant to 1 or more previous lines of treatments (which must include a Tyrosine Kinase Inhibitor)

Exclusion

  • Collecting duct histology
  • A history of bleeding disorders or currently taking oral vitamin K antagonise medication
  • Unstable brain metastases
  • History of prior or concomitant malignancy (except for curatively treated non-melanoma skin cancer or carcinoma in situ of the cervix, or other cancer for which the patient has been disease free for 3 years)

Key Trial Info

Start Date :

August 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2010

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00740441

Start Date

August 1 2008

End Date

March 1 2010

Last Update

September 25 2009

Active Locations (7)

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Page 1 of 2 (7 locations)

1

City of Hope

Duarte, California, United States, 91010

2

University of California, Davis Cancer Center

Sacramento, California, United States, 95817

3

University of California San Francisco

San Francisco, California, United States, 94143

4

St Francis Hospital

Beech Grove, Indiana, United States, 46107