Status:
COMPLETED
Radiolabeled Glass Beads Used for Treating Patients With Primary Liver Cancer When Surgery is Not an Option
Lead Sponsor:
OHSU Knight Cancer Institute
Collaborating Sponsors:
Oregon Health and Science University
Boston Scientific Corporation
Conditions:
Liver Cancer
Hepatoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fewer than 15% of hepatoma patients are suitable candidates for surgical removal of their cancer. The purpose of this protocol is to provide supervised access at Oregon Health and Science University t...
Detailed Description
Patients receive Y-90 (yttrium) glass microspheres via percutaneous hepatic arterial infusion. Patients amy be retreated between 30-90 days after initial infusion. After completion of therapy, patient...
Eligibility Criteria
Inclusion
- Confirmed diagnosis of HCC
- Cancer is unresectable
- ECOG Score 0-2
- Age of 18 yrs or over
- Able to give consent
Exclusion
- Contraindication to angiography and selective visceral catheterization
- Portal hypertension with portal venous shunt away from the liver
- Evidence of potential delivery of \> 16.5 mCi of radiation to the lungs
- Evidence of any detectable Tc-99m MAA flow to the stomach or duodenum, after application of established angiographic techniques to stop such flow
- Significant extrahepatic disease representing an imminent life-threatening outcome
- Severe liver dysfunction or pulmonary insufficiency
- Active uncontrolled infection
- Significant underlying medical or psychiatric illness
- Pregnancy
Key Trial Info
Start Date :
August 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 28 2021
Estimated Enrollment :
339 Patients enrolled
Trial Details
Trial ID
NCT00740753
Start Date
August 1 2004
End Date
April 28 2021
Last Update
September 30 2022
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