Status:

WITHDRAWN

Effect of PTH(1-34) Treatment on Fracture Healing in Vivo

Lead Sponsor:

Glostrup University Hospital, Copenhagen

Collaborating Sponsors:

The Danish Medical Research Council

Conditions:

Shoulder Fractures

Trochanteric Fractures

Eligibility:

FEMALE

50-85 years

Phase:

PHASE2

Brief Summary

The purpose of the study is to investigate, whether PTH(1-34) is able to promote fracture healing in postmenopausal women with fractures of the hip or shoulder.

Eligibility Criteria

Inclusion

  • Acute new osteoporotic trochanteric or collum chirurgicum fracture
  • Postmenopause

Exclusion

  • Calcium metabolic disease other than osteoporosis
  • Diseases known to affect calcium homeostasis
  • Dementia
  • Hypersensitivity to drug or other components of medication
  • pre-existing hypercalcemia
  • Decreased kidney function
  • Increased alkaline phosphatase
  • Prior external radiation therapy or brachytherapy of the skeleton
  • Skeletal malignancies or bone metastases
  • Alcohol and/or drug abuse
  • Systemic treatment with corticosteroids within the last four weeks
  • Non-cooperating patients
  • Patients who do not speak and understand the danish language

Key Trial Info

Start Date :

October 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2010

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00741182

Start Date

October 1 2008

End Date

September 1 2010

Last Update

March 18 2015

Active Locations (1)

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1

Research Center for Ageing and Osteoporosis, Glostrup University Hospital

Copenhagen, Denmark