Status:
COMPLETED
Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder
Lead Sponsor:
University of Maryland, Baltimore
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Depression
Eligibility:
All Genders
18-64 years
Brief Summary
This study will evaluate a possible tool for predicting future effectiveness of bright light in treating seasonal affective disorder, winter subtype, and will examine secondary effects of bright light...
Detailed Description
The winter subtype of seasonal affective disorder (SAD) is characterized by episodes of major depression in the fall and winter, with remission of these episodes in the spring and summer. SAD disrupts...
Eligibility Criteria
Inclusion
- Current major depressive disorder, by structured diagnostic interview (SCID), or current bipolar II disorder, if no prior history of rapid cycling, by SCID
- Prior history of major depressive disorder or bipolar II disorder with seasonal specifier, by SCID
- Score of 21 or greater on Hamilton Rating Scale for Depression - Seasonal Affective Disorder Version (SIGH-SAD), met at three time points (informed consent session, 24 hours prior to first light therapy session, and at first light therapy session)
Exclusion
- Current bipolar I disorder, psychotic disorder, or cognitive disorder, by SCID
- Illicit drug use in the past year, by self-report, or alcohol abuse by SCID
- History of systemic lupus erythematosus
- History of heart attack or stroke
- No antidepressant, mood stabilizer, or antipsychotic medication treatment 30 days before treatment
- Current occupation involves shift work
- Current sensitivity to bright light or vision problems not correctable by glasses, by self-report
- Inability to distinguish colors or see stars at night because of increased light sensitivity, by self-report
- Current suicidal ideation, by self-report during SCID interview
- Women of childbearing potential who are pregnant, nursing, or trying to become pregnant. Female participants of childbearing potential must agree to one of the following types of birth control: oral, transdermal, or implantable hormonal contraceptives; intrauterine device; diaphragm plus spermicide; or female condom plus spermicide.
Key Trial Info
Start Date :
November 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT00742365
Start Date
November 1 2007
End Date
August 1 2010
Last Update
November 21 2019
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