Status:

COMPLETED

Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q.3

Lead Sponsor:

Vanderbilt University

Conditions:

Type 1 Diabetes

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

It has been found that in some cases, when a person with Diabetes Mellitus has an episode of low blood sugar,or hypoglycemia, and then later exercises, he or she is vulnerable to another bout of hypog...

Detailed Description

The SPECIFIC AIM of the study outlined in this proposal is to determine if hypoglycemia blunts counterregulatory responses during subsequent exercise in Type 1 Diabetes Mellitus due to physiologic inc...

Eligibility Criteria

Inclusion

  • Males and females with Type 1 Diabetes Mellitus will be studied. Subjects recruited will be 18-50 years, with an HBA1c less than 9.5%, who have been diagnosed with diabetes for \>5 years, with no clinical evidence of diabetic tissue complications.

Exclusion

  • Subjects with known prior cardiac events will be excluded from the study. Additional exclusion criteria:
  • all medical students (Vanderbilt policy)
  • prior or current history of poor health
  • abnormal results following blood and physical examination
  • pregnancy

Key Trial Info

Start Date :

March 1 2001

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT00742521

Start Date

March 1 2001

End Date

June 1 2009

Last Update

June 10 2015

Active Locations (1)

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Vanderbilt University

Nashville, Tennessee, United States, 37232