Status:
COMPLETED
Stress, Hypothalamic-pituitary-adrenal (HPA) Dysfunction, and Relapse in Alcoholism
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
Dallas VA Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Alcohol Dependence
Eligibility:
MALE
18-60 years
Brief Summary
This proposal is part of the INIA Stress Consortium. This study will 1. explore the contributions of lifetime trauma, recent stress, and alcohol use on stress-hormone axis disruption in treatment see...
Detailed Description
The hypothalamic-pituitary-adrenal (HPA) system is suggested as a key biologic link in stress-induced relapse. The HPA axis provides a regulatory feedback network between the brain and the body's beha...
Eligibility Criteria
Inclusion
- Diagnosis of alcohol dependence
Exclusion
- Medical or psychiatric disorders that may effect stress-hormone axis functioning.
- Medications that may effect stress-hormone axis functioning.
- English speaking.
Key Trial Info
Start Date :
August 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00744588
Start Date
August 1 2007
End Date
March 1 2012
Last Update
January 3 2013
Active Locations (1)
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1
UT Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390-8564