Status:

COMPLETED

The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation

Lead Sponsor:

University of Edinburgh

Collaborating Sponsors:

Umeå University

Conditions:

Heart Disease

Eligibility:

MALE

18-35 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether a retrofit particle trap can reduce the adverse vascular responses to diesel exhaust inhalation

Detailed Description

18 subjects healthy male volunteers will be recruited at Umeå University. In a randomised, double blind 3 way crossover trial, subjects will be exposed to filtered air, diesel exhaust (300mcg/m3) or f...

Eligibility Criteria

Inclusion

  • Healthy male volunteers

Exclusion

  • Intercurrent illness
  • Smoking
  • Significant occupational exposure to air pollution
  • Regular medication usage

Key Trial Info

Start Date :

September 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2008

Estimated Enrollment :

18 Patients enrolled

Trial Details

Trial ID

NCT00745446

Start Date

September 1 2007

End Date

February 1 2008

Last Update

September 5 2008

Active Locations (1)

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Umeå University

Umeå, Västerbottens, Sweden, SE-901 87