Status:
COMPLETED
Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
AstraZeneca
Conditions:
Vasomotor Rhinitis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis
Eligibility Criteria
Inclusion
- age between 18-80, symptoms of perennial rhinitis, negative epicutaneous skin testing to a panel of common aeroallergens, and ability to speak English
Exclusion
- pregnancy or breast-feeding, evidence of positive skin tests to a common aeroallergen, treatment with a proton pump inhibitor within the month prior to enrollment, treatment with any other anti-reflux therapy within the last month on a daily basis or within the last two weeks on an as needed basis, and other gastrointestinal disorders leading to reflux symptoms
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2008
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT00745849
Start Date
June 1 2005
End Date
March 1 2008
Last Update
June 11 2019
Active Locations (1)
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1
Clinical Trials Office, Aston Building, UT Southwestern
Dallas, Texas, United States, 75390-9016