Status:

TERMINATED

Feasibility Study of Simvastatin in Hodgkin's Lymphoma Survivors

Lead Sponsor:

Columbia University

Collaborating Sponsors:

Children's Hospital of Philadelphia

Conditions:

Carotid Artery Disease

Eligibility:

All Genders

18-35 years

Phase:

NA

Brief Summary

Lay abstract: Study Purpose With contemporary combined modality therapy the expected longterm survival of children and adolescents with Hodgkin's disease (HD) is exceedingly high. Thus, the emphasis f...

Detailed Description

With contemporary combined modality therapy the expected longterm survival of children and adolescents with Hodgkin's disease (HD) is exceedingly high. Thus, the emphasis for future therapeutic interv...

Eligibility Criteria

Inclusion

  • At least three years from completion of treatment for Hodgkin's Disease
  • Age 18- 35
  • Ability to complete self report questionnaires in either English or Spanish
  • Willingness of patient, or parent/guardian if patient less than 18 years of age to sign consent to participate in study
  • Willingness of patient to sign assent if greater than 7 years of age and less than 18 years

Exclusion

  • Pregnant or breast feeding
  • Tanner Stage 1
  • Currently taking cyclosporine, niacin, antiretrovirals, macrolide antibiotic, azole antifungal
  • Liver enzymes greater than 1.5 times the upper level of normal
  • Creatine Kinase greater than 2 times the upper level of normal
  • Use of estrogen containing contraceptive

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT00746603

Start Date

January 1 2008

End Date

July 1 2009

Last Update

March 2 2021

Active Locations (1)

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1

Columbia Univeristy Medical Center

New York, New York, United States, 10032