Status:
COMPLETED
Efficacy of Purslane in Treatment of Oral Lichen Planus
Lead Sponsor:
Qazvin University Of Medical Sciences
Conditions:
Lichen Planus, Oral
Eligibility:
All Genders
25-70 years
Phase:
PHASE2
Brief Summary
Oral lichen planus (OLP) is a chronic inflammatory disease whose prevalence in the general population is 0.5 -2.2%.Oral lesions in OLP are chronic, rarely undergo spontaneous remission. Patients with ...
Detailed Description
Oral lichen planus is a chronic common inflammatory disorder affecting stratified squamous epithelia. The majority problem of OLP is development of oral squamous cell carcinoma , irrespective of the c...
Eligibility Criteria
Inclusion
- Biopsy confirmed symptomatic oral lichen planus: WHO histological criteria in combination with clinical appearance will be used for diagnosis
- Patients who had symptoms such as burning sensation, pain
- Patients not on any immunosuppressive or immunomodulatory treatment. In case they were,then such treatment should be stopped and a washout period of 1 month was given.
- Patients of both sexes between 30 to 70 year's old
- Patients who gave written informed consent
- Patients who were willing for evaluation in second week after therapy and every 1 month up to 6 months
Exclusion
- The presence of histological signs of dysplasia
- Patients suffering from any localized or systemic disease
- Renal disease patients
- Pregnant patients
- Patients who can not continue the study for private or social reasons
- Patients who used lichenoid reaction including drugs
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2008
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT00746772
Start Date
April 1 2006
End Date
August 1 2008
Last Update
September 8 2010
Active Locations (1)
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1
Qazvin university of medical sciences
Qazvin, Qazvin Province, Iran, 3415759811