Status:
COMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life
Lead Sponsor:
University of Utah
Conditions:
Preterm and Term Infants
Eligibility:
All Genders
Up to 48 years
Brief Summary
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study. 1) To complemen...
Detailed Description
S100B is a low molecular weight calcium binding protein found predominantly in the central nervous system (CNS), specifically astroglial cells.\[1\] S100B plays a role in calcium-dependent information...
Eligibility Criteria
Inclusion
- Infants born at \>28 weeks gestation will be eligible for enrollment in this study.
Exclusion
- Infants with fetal malformations, chromosomal anomalies, clinically significant sepsis (retractable hypotension, neutropenia, and thrombocytopenia), or no urine output for the first 48 hours will be excluded.
Key Trial Info
Start Date :
April 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2007
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT00747864
Start Date
April 1 2006
End Date
January 1 2007
Last Update
July 23 2010
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