Status:
COMPLETED
Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions:
Arthritis, Rheumatoid
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthri...
Detailed Description
The objective of this proposal is to adapt photoacoustic tomography (PAT), a novel, nonionizing, noninvasive, laser-based technology, for structural and functional imaging of human peripheral joints a...
Eligibility Criteria
Inclusion
- Men and women 18 years of age or older can participate in this study.
- Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study.
- Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis.
Exclusion
- Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
- Pregnant patients.
- Patients who is claustrophobic.
- Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc.
- Patients with shock hypotension or unstable low blood pressure.
- Patients with Rhabdomyolysis.
- Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).
Key Trial Info
Start Date :
December 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 13 2025
Estimated Enrollment :
113 Patients enrolled
Trial Details
Trial ID
NCT00748254
Start Date
December 1 2011
End Date
May 13 2025
Last Update
July 28 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Universtity of Michigan Health System
Ann Arbor, Michigan, United States, 48109