Status:
COMPLETED
Effect of Lactobacillus Probiotic on Healthy Adults
Lead Sponsor:
Fargo VA Medical Center
Conditions:
Antibiotic-associated Diarrhea
Eligibility:
All Genders
18-64 years
Phase:
PHASE1
Brief Summary
Diarrhea is a common side effect of antibiotics; it may prolong hospital stay, increase the risk of other infections, develop into more serious forms of disease, and lead to premature discontinuation ...
Eligibility Criteria
Inclusion
- Participants (male or female inpatients) 18 to 64 years of age who are prescribed antibiotics (single or multiple antibiotics, oral or intravenous) will be recruited from the Fargo VAMC Primary Care Clinic area.
- Participants must be able to swallow a capsule.
Exclusion
- Exclusion criteria include diarrhea on admission or within the preceding week
- Reported recurrent diarrhea
- Antibiotics in the past four weeks
- Significant underlying conditions (e.g. diabetes, structural cardiac defects including valvular defects, history of infective endocarditis, poor cardiac function, immunosuppression, impaired gut integrity, moderate or serious intestinal disorders, malignancies, pancreatitis, indwelling catheters, recent surgery, recent prolonged hospitalization)
- Previous bowel surgery
- Nutritional restrictions that preclude participation
- Hypersensitivity to penicillin G, ampicillin, or erythromycin
- Persons who have been prescribed their antibiotic for a duration longer than 3 weeks
Key Trial Info
Start Date :
February 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00748748
Start Date
February 1 2010
End Date
April 1 2012
Last Update
July 4 2012
Active Locations (1)
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1
Fargo VA Medical Center
Fargo, North Dakota, United States, 58102