Status:

COMPLETED

Biodistribution of Neutrophile Proteases in the Sputum of Patients Affected by Cystic Fibrosis

Lead Sponsor:

University Hospital, Tours

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

6+ years

Brief Summary

The purpose of the proposed project is to characterize the neutrophile proteases which participate in the chronic inflammatory phenomenon associated with the cystic fibrosis and which are responsible ...

Eligibility Criteria

Inclusion

  • Man /woman older than 18 years (for adult and group)
  • Child aged 6 to 18 years (for child group)
  • Suffering from cystic fibrosis in stable condition, ie not having presented thrust acute attack of the broncho-pulmonary or hospitalization for treatment of his illness during the previous 2 weeks

Exclusion

  • colonized by Burkholderia cepacia ou Stenotrophomonas maltophilia
  • non smoker (control group)
  • Without history or respiratory respiratory disease known (control group)
  • Antibiotic treatment and / or anti-inflammatory drug (NSAID or corticosteroids) in the 2 weeks prior to the inclusion in the study (control group)

Key Trial Info

Start Date :

January 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2012

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT00750932

Start Date

January 1 2008

End Date

January 1 2012

Last Update

February 27 2017

Active Locations (1)

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CHRU de Tours

Tours, France, 37044