Status:
UNKNOWN
Stereotactic Aspiration and Thrombolysis of Intracerebral Hemorrhage: a Prospective Controlled Study
Lead Sponsor:
Huazhong University of Science and Technology
Conditions:
Hypertensive Intracerebral Hemorrhage
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the superiority of effect of the modified micro-invasive aspiration and drainage and conservative medical therapy in the treatment of ICH spontaneously hyperte...
Detailed Description
The stereotactic computed tomographic-guided aspiration and drainage is one of the best choices in the treatment of a large-scale deep supratentorial intracerebral hematoma. It uses hardware access te...
Eligibility Criteria
Inclusion
- CT diagnosis of spontaneous supratentorial intracerebral hemorrhage, the amount of bleeding more than 50 ml, and had neurological signs
- All income groups the incidence of medical records to be random, the time should be \< 69 hours to ensure that within 72 hours of the onset of the operation
- To be random, former GCS score \> = 5 points
- Systolic blood pressure \<= 200 mmHg, mean arterial pressure \<= 150 mmHg (if higher than this value, but as corresponding to this standard can be dealt with the group, and only reached the standard before they can ask for random)
- Fasting plasma glucose \<= 11.1 mmol / L (if higher than this value, but as corresponding to this standard can be dealt with the group, and only reached the standard before they can ask for random)
- Patients aged 18 to 80-year-old.
- Based on China's relevant laws, the patient himself or family members (only in patients with the loss of his ability to judge the acts of circumstances) agreed to participate in this study, a good compliance, to fully comply with random, in accordance with the decision by the treatment, patients himself Or family members must sign informed consent moreover.
- Patients themselves or their families (only in patients with the loss of his ability to judge the acts of circumstances) have willingness and ability to follow the research program, data collection and preservation of history and follow-up process of informed consent.
Exclusion
- Patients clotting mechanisms are obstacles or having the experience of the use of anticoagulant drug (PT\> 15s, APTT\> 40s, INR\> 1.4, platelet count \<100 × 10 9 / L).
- Cerebral hernia formed more than two hours
- The merger of other serious system failure (heart, liver and kidney, etc.) or a variety of end-stage disease with cerebral hematoma (such as renal failure late cerebral hemorrhage, blood disease with cerebral hemorrhage)
- Prior to the onset of a variety of reasons for the defect or neurological movement disorder
- A clear cause of cerebral hemorrhage such as intracranial aneurysm, or dynamic
- such as a venous malformation
- Intracranial or serious systemic infection
- Marked cognitive impairment or mental abnormality
- Other such as pregnancy, cancer
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2010
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00752024
Start Date
September 1 2008
End Date
December 1 2010
Last Update
September 15 2008
Active Locations (1)
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1
Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030