Status:
COMPLETED
The Effects of Epinephrine in Endotoxemia in Normal Volunteers
Lead Sponsor:
Rutgers, The State University of New Jersey
Conditions:
Immune System
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
Epinephrine (adrenaline) is a substance produced by the body (in the adrenal gland) in response to stress such as infection or injury. Endotoxin is a man- made substance, which causes the body to "mim...
Detailed Description
The body's immune response to injury otr infection is very complex. immune cell activity, the release of specific mediators (such as proteins), genetics (Deoxyribonucleic acid or DNA) and/or the body'...
Eligibility Criteria
Inclusion
- General good health as demonstrated by medical history, physical\& laboratory tests
- Age between 18 and 40 years
- Written informed consent prior to the performance of any study related procedures
Exclusion
- History of cancer, rheumatoid arthritis, or immunological, renal, hepatic, endocrine, neurologic, heart disease or hypertension
- Any medication taken in past 48 hrs (except birth control)
- Recent history of alcohol or drug abuse
- Unable to provide written informed consent
- Exposure to any experimental agent or procedure within 30 days of study
- Pregnant or breast-feeding
Key Trial Info
Start Date :
February 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT00753402
Start Date
February 1 2012
End Date
February 1 2012
Last Update
May 27 2015
Active Locations (1)
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1
Rutgers-RWJMS
New Brunswick, New Jersey, United States, 08901