Status:
COMPLETED
Pharmacokinetics and Safety of Intravenous Topiramate in Adult Patients
Lead Sponsor:
University of Minnesota
Conditions:
Epilepsy
Migraines
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The aims of this study are to determine, in adult patients on maintenance topiramate therapy, the steady-state pharmacokinetics and safety of orally and intravenously administered topiramate.
Detailed Description
The long-term goal of this research project is to develop a more effective, safer therapy for neonatal seizures. Prior to using an investigational intravenous topiramate formulation in children and ne...
Eligibility Criteria
Inclusion
- Persons taking topiramate
- Persons 18 years of age and older
Exclusion
- Patients who are pregnant
- Patients who are breast feeding
- Patients with significant medical problems who may not tolerate intravenous administration
- Patients taking medications known to affect topiramate disposition
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00753493
Start Date
August 1 2008
End Date
August 1 2010
Last Update
July 18 2019
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455