Status:
COMPLETED
Molecular Studies on the Candidate Genes of Dopaminergic and Noradrenergic Systems in ADHD
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
National Science and Technology Council, Taiwan
Conditions:
Attention Deficit Hyperactivity Disorder
Eligibility:
All Genders
7-18 years
Brief Summary
The ultimate goal of this study is to find specific polymorphism of candidate genes associated with endophenotypes and/or phenomenological phenotypes of ADHD. We propose to replicate the analysis of t...
Detailed Description
Attention deficit hyperactivity disorder (ADHD), characterized by inattention, hyperactivity and impulsivity, is an early onset, highly heritable, clinically heterogeneous, long-term impairing disorde...
Eligibility Criteria
Inclusion
- The inclusion criteria for the proband subjects are
- That subjects have a clinical diagnosis of ADHD, or Hyperkinetic Disorder defined by the DSM-IV and ICD-10, respectively, which was made by a full-time board-certificated child psychiatrist at the first visit and following visits;
- Their ages range from 7 to 18 when we conduct the study;
- Subjects have at least one biological parent;
- Both parents are Han Chinese;
- Subjects and their biological parents (and siblings if any) consent to participate in this study for complete phenotype assessments and blood withdraw or saliva collection for genetic study.
Exclusion
- The proband subjects will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV:
- Schizophrenia,
- Schizoaffective Disorder,
- Organic Psychosis, or Pervasive Developmental Disorder.
- Moreover, the subjects will also be excluded from the study if they completely cannot cooperate with blood withdrawal, collection of saliva, or buccal swabs.
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2011
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00756158
Start Date
August 1 2008
End Date
July 31 2011
Last Update
September 5 2021
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan