Status:
COMPLETED
HOP-2A - Intratesticular Hormone Levels
Lead Sponsor:
University of Washington
Conditions:
Healthy
Male Infertility
Eligibility:
MALE
18-50 years
Brief Summary
The purpose of this investigational study is to find out what hormones are present in healthy male testicles using fine needle aspiration.
Detailed Description
We will collect a very small amount of fluid from each testicle. Participation will last up to 12 weeks. The study involves a minimum of 4 visits, the screening visit and procedure Day, fine needle as...
Eligibility Criteria
Inclusion
- males between 18 and 50 years of age
- sperm count greater than 20 million/ml, greater than 50% motility, and greater than 15% normal morphology
- in good general health based on normal screening evaluation (consisting of a medical history, physical exam, normal sperm count, normal serum chemistry, hematology and baseline T, LH, and FSH levels)
- body mass index ≥18 and ≤32 kg/m2
- must agree not to participate in another research study involving drug exposure for the duration of the study
Exclusion
- men in poor general health, with abnormal blood results
- sperm counts \<20 million/ml on two tests
- chronic, ongoing alcohol or drug abuse
- participation in a long-term male contraceptive study within the past three months
- history of testicular or scrotal surgery
- history of infertility
- abnormal testicular exam
- abnormal DRE
- chronic pain syndrome
- use of steroids, testosterone, or medications which might interfere with androgen metabolism including ketoconazole, glucocorticoids
- known bleeding disorder
- use of medications which may affect bleeding time (ongoing aspirin or anti-inflammatory use, coumadin)
Key Trial Info
Start Date :
September 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00756561
Start Date
September 1 2008
End Date
December 1 2009
Last Update
June 13 2016
Active Locations (1)
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1
University of Washington
Seattle, Washington, United States, 98195