Status:

COMPLETED

The Impact of Osmotic Release Oral Delivery System Methylphenidate (OROS MPH) Upon Family of Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)

Lead Sponsor:

Johnson & Johnson Taiwan Ltd

Conditions:

Attention Deficit Disorder With Hyperactivity

Eligibility:

All Genders

6-18 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate whether familial relationships and psychological status of participants or caregivers as well as Attention Deficit Hyperactivity Disorder (ADHD) symptoms of pa...

Detailed Description

This is a prospective (study following participants forward in time), single-arm, open-label (all people know the identity of the intervention), 8-week, multi-centric (conducted in more than 1 center)...

Eligibility Criteria

Inclusion

  • Participants who are diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)
  • Participants who have been treated with Immediate-release methyphenidate (IR-MPH) for at least 4 weeks before enrollment, but previous treatment is considered unsatisfactory due to 1 or more of the following reasons: lack of effectiveness, lack of tolerability or safety, lack of compliance, and/or other reasons
  • Participants who are able to comply with the study visit schedule and whose parents/caregiver and community school teacher are willing and able to complete the protocol-specified assessments
  • Participants who are still at school
  • Participants who are treated with greater than equal to 10 milligram (mg) IR-MPH daily before enrollment

Exclusion

  • Participants who cannot understand or follow the instructions given in the study
  • Participants with serious or unstable medical illness
  • Participants who have clinically significant gastrointestinal problems, including narrowing of the gastrointestinal tract
  • Participants who have glaucoma (increased pressure inside the eye that causes visual problems), an ongoing seizure disorders, or a psychotic disorder
  • Participants who are hypersensitive to methylphenidate
  • Participants who have any co-existing medical condition or are taking a concomitant medication that is likely to interfere with safe administration of methylphenidate

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

296 Patients enrolled

Trial Details

Trial ID

NCT00758160

Start Date

March 1 2008

End Date

June 1 2008

Last Update

April 8 2014

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The Impact of Osmotic Release Oral Delivery System Methylphenidate (OROS MPH) Upon Family of Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD) | DecenTrialz