Status:
COMPLETED
Effect of Stress on Heroin-Related Memory Retrieval
Lead Sponsor:
National Institute on Drug Dependence, China
Conditions:
Heroin Dependence
Learning and Memory
Eligibility:
MALE
20-40 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether cortisol and propranolol are effective in the modulation of stress induced heroin-related retrieval enhancement.
Eligibility Criteria
Inclusion
- Participants had to have met DSM-IV criteria for heroin dependence prior to abstinence.
Exclusion
- current use of any medications; current DSM-IV diagnosis of any affective, anxiety, or psychotic disorder; current dependence on any substance besides heroin and nicotine (based on DSM-IV criteria); or risk factors for untoward side effects from propranolol and cortisol (i.e., irregular heartbeats, history of cardiogenic shock, history of severe heart failure, asthma, fungal Infections, hyperlipidemia, history of hypertension, or abnormal ECG or other laboratory findings).
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
End Date :
September 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00759005
Start Date
March 1 2007
End Date
September 1 2008
Last Update
September 25 2008
Active Locations (1)
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1
National Institute on Drug Dependence
Beijing, Beijing Municipality, China, 100191