Status:
COMPLETED
The Role of Mineralocorticoid Receptors in Vascular Function
Lead Sponsor:
Brigham and Women's Hospital
Conditions:
Apparent Mineralocorticoid Excess (AME)
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to figure out how decreasing the activity of 11-beta hydroxysteroid dehydrogenase (11-beta HSD) will affect your blood vessel function. 11-beta HSD, which is found in the ...
Detailed Description
This study intends to determine whether activation of mineralocorticoid receptors affects vascular function. Vascular function relies on two components of the blood vessel: the inner lining (endotheli...
Eligibility Criteria
Inclusion
- Healthy volunteers
Exclusion
- Blood pressure above 140/90
- Abnormal physical finding
- Blood test values for total and LDL cholesterol, CBC, sodium, potassium, creatinine, and glucose laboratories greater 1.5 times normal
Key Trial Info
Start Date :
February 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00759525
Start Date
February 1 2002
End Date
September 1 2009
Last Update
October 26 2016
Active Locations (1)
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1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115