Status:
COMPLETED
The Role of Parathyroid Hormone (PTH) in Low Bone Mass in Anorexia Nervosa
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
Eli Lilly and Company
Conditions:
Anorexia Nervosa
Osteoporosis
Eligibility:
FEMALE
30-70 years
Phase:
PHASE2
Brief Summary
Decreased bone strength is a common and serious medical problem present in many women with anorexia nervosa, or disordered eating. Women with decreased bone strength are more likely to suffer broken b...
Detailed Description
Anorexia Nervosa affects 0.5-1% of college-age women in the US and is associated with a number of significant medical conditions including bone loss. A majority of women with anorexia nervosa have bon...
Eligibility Criteria
Inclusion
- Anorexia Nervosa
- Women, age 30-70 years
- Osteoporosis or history of clinical fractures (spine, wrist, hip or ribs)
Exclusion
- Diseases known to affect bone metabolism
- Hyperparathyroidism
- Medications known to affect bone metabolism in last 12 weeks (or bisphosphonate use in last 1 year)
- Pregnant and/or breastfeeding
- Diabetes mellitus
- History of malignancy involving or affecting the bone, any active malignancy, and/or radiation therapy to the bone
- Fractures of a bone other than a finger or toe in last 1 year
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 22 2016
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT00759772
Start Date
September 1 2008
End Date
February 22 2016
Last Update
May 11 2017
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114