Status:
WITHDRAWN
Lipopolysaccharide Binding Protein and Development of Infectious Events in Cirrhotic Patients
Lead Sponsor:
Florencia Vargas-Vorackova
Collaborating Sponsors:
Laboratorios Senosiain, S.A. de C.V.
Conditions:
Cirrhosis
Ascites
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether plasma levels of lipopolysaccharide binding protein (LBP) are correlated with PBMN pro- and anti-inflammatory cytokine secretion, as well as with the ...
Eligibility Criteria
Inclusion
- Cirrhosis
- Ascites
- No history of spontaneous bacterial peritonitis and/or \< 1 g of protein in ascites
- No antibiotic use in previous 6 weeks
- Absence of infection (documented by clinical history, blood cytology, urinalysis and urine culture, thorax x-ray and paracentesis)
- Absence of GI bleeding or encephalopathy
- Signature of informed consent
Exclusion
- Ciprofloxacin contraindication
- Autoimmune hepatitis, sclerosing cholangitis or other autoimmune disease
- \> 13 Child-Pugh points
- Inability to attend to regular visits
- Current alcohol intake
- Terminal disease with \< 24 week expected survival
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00760032
Last Update
December 5 2012
Active Locations (1)
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1
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
México, D.f., Mexico, 14000