Status:

COMPLETED

Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)

Lead Sponsor:

Alcon Research

Conditions:

Angle-closure Glaucoma

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to demonstrate that the Intraocular Pressure (IOP) lowering efficacy of Travoprost Ophthalmic Solution 0.004% is superior to that of Pilocarpine 1% in patients with chroni...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • Chronic Angle Closure Glaucoma (CACG)
  • 21-35 millimeters mercury mean intraocular pressure on Eligibility visit day at 9 AM
  • Peripheral iridotomy performed ≥ 1 Month prior to the Screening visit
  • Anterior chamber angle in which the trabecular meshwork is not visible for ≥180 degrees in gonioscopy without indentation
  • Peripheral anterior synechiae (PAS)

Exclusion

  • Traumatic damage of the anterior chamber angle
  • History of ocular inflammation or surgery (except for iridotomy) ≤ 3 months
  • Patients who cannot be safely discontinued from use of all ocular hypotensive medication(s) for 12 days to 14 weeks
  • Visual Acuity ≥ 1.0
  • Contact lenses wearer

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00762645

Start Date

February 1 2007

End Date

May 1 2008

Last Update

December 6 2023

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