Status:
TERMINATED
The Use of Sensory or Motor Cues Using Electrical Stimulation to Reduce Gait Freezing in Patients With Parkinson Disease
Lead Sponsor:
Washington University School of Medicine
Conditions:
Parkinson Disease
Eligibility:
All Genders
50-80 years
Phase:
EARLY_PHASE1
Brief Summary
Some individuals with Parkinson disease experience "freezing" during walking which results in their inability to move their feet. They often have difficulty starting to move once they have stopped. Fr...
Detailed Description
We will use a device (TENS unit) that provides electrical stimulation to a nerve in the lower legs. Electrodes will be placed on the skin of your lower legs and a box that delivers electrical current ...
Eligibility Criteria
Inclusion
- PD diagnostic criteria include those used for clinically defined "definite PD", as previously outlined22 based upon established criteria.22, 23
- history of consistent freezing with ambulation in a straight line and/or when turning.
- normal central and peripheral neurological function
- at least grade 4 strength and normal joint ranges of motion in both legs
- normal somatosensory function in the feet (joint position sense), except for their neurological diagnosis and use of levodopa.
- Each must have had clear benefit from levodopa for at least some of his/her PD symptoms
- All subjects with PD must be able to walk independently for 10 feet.
Exclusion
- serious medical problem that would impair the ability to undergo testing.
- use of neuroleptic or other dopamine-blocking drug
- use of drugs that might affect balance
- history or evidence of other neurological deficit that could interfere, such as previous stroke or muscle disease
- participants who are unable to provide informed consent
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT00762814
Start Date
May 1 2008
End Date
June 1 2009
Last Update
May 11 2018
Active Locations (1)
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1
Washington University Program in Physical Therapy
St Louis, Missouri, United States, 63108