Status:

COMPLETED

Effect of Weight-Bearing Exercise on People With Diabetes and Neuropathic Feet

Lead Sponsor:

Washington University School of Medicine

Conditions:

Diabetes Mellitus

Peripheral Neuropathy

Eligibility:

All Genders

40-90 years

Phase:

NA

Brief Summary

The purpose of this study is to determine if people with Diabetes Mellitus and peripheral neuropathy can increase their activity (i.e. walking or stationary biking) and leg strength without having an ...

Detailed Description

People with diabetes and peripheral neuropathy (DM+PN) have substantial lower extremity impairments, functional limitations and disability. In addition to muscle weakness and poor balance, they also a...

Eligibility Criteria

Inclusion

  • Type 1 or Type 2 DM and PN
  • biothesiometer \> 25mV and
  • unable to sense the 5.07 Semmes Weinstein monofilament on at least one spot on the plantar foot
  • Relatively sedentary
  • step count of 2-9,000 steps per day
  • exercising less than 3 times per week (\<20 min/session).
  • Have the approval of his/her primary care physician to participate in the study.

Exclusion

  • Subjects who weigh greater than 300 pounds (DXA scanner's weight limit).
  • A history of severe foot deformity, such as Charcot neuroarthropathy or partial foot amputation that would require custom therapeutic footwear.
  • Any co-morbidity or medication that would interfere with ability to exercise according to ADA and ACSM guidelines.
  • People with severe depression as determined by the Beck Depression Inventory II with a score of 29 or greater.
  • People who are physically incapable of tolerating one hour of activity.
  • Women of child bearing age due to risk of exposure from radiation in DXA testing.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2011

Estimated Enrollment :

43 Patients enrolled

Trial Details

Trial ID

NCT00763087

Start Date

September 1 2008

End Date

January 1 2011

Last Update

November 7 2017

Active Locations (1)

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Program in Physical Therapy, Washington University in St. Louis

St Louis, Missouri, United States, 63108