Status:
COMPLETED
A Study of Transcranial Direct Current Stimulation (tDCS) to Treat Depression
Lead Sponsor:
The University of New South Wales
Conditions:
Depressive Disorder, Major
Bipolar Disorder
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
PHASE3
Brief Summary
Depression is a common illness with an approximate lifetime prevalence of 17 %, conferring a large burden of disease in the community, often due to inadequate treatment. Thus there is interest in the ...
Eligibility Criteria
Inclusion
- Meets criteria for DSM-IV Major Depressive Episode
Exclusion
- Diagnosis (as defined by DSM-IV) of: any psychotic disorder except bipolar disorder(lifetime); eating disorder (current or within the past year); obsessive compulsive disorder (lifetime); post-traumatic stress disorder (current or within the past year); mental retardation.
- History of drug or alcohol abuse or dependence (as per DSM-IV criteria) within the last 3 months (except nicotine and caffeine).
- Inadequate response to ECT in the current episode of depression.
- Subject is on regular benzodiazepine medication which it is not clinically appropriate to discontinue.
- Subject requires a rapid clinical response due to inanition, psychosis or high suicide risk.
- Neurological disorder or insult, eg recent stroke (CVA), which places subject at risk of seizure or neuronal damage with tDCS.
- Subject has metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites.
- Female subject who is pregnant, or of child-bearing age, sexually active and not using reliable contraception
Key Trial Info
Start Date :
April 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2011
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT00763230
Start Date
April 1 2008
End Date
January 1 2011
Last Update
May 2 2011
Active Locations (1)
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1
Black Dog Institute, University of New South Wales
Randwick, New South Wales, Australia, 2031