Status:
COMPLETED
Ghrelin Changes After Roux-en-Y Gastric Bypass
Lead Sponsor:
Vanderbilt University
Conditions:
Obesity
Insulin Resistance
Eligibility:
All Genders
18-60 years
Brief Summary
The purpose of this study is to determine whether gastric division (via Roux-en-Y gastric bypass) with resultant fundic isolation will alter the pattern(s) of Ghrelin secretion in the early post-opera...
Eligibility Criteria
Inclusion
- Serum creatinine and liver function tests \< upper limits of normal
- Stable body weights for the past three months
- Women will have a negative pregnancy test
- patients who are already scheduled for RYGB with gastrostomy tube placement
Exclusion
- Significant hepatic enzyme elevations (more than 100% of upper limits of normal)
- Serum creatinine \> 1.5 mg/dl
- history of ketoacidosis or current metabolic acidosis
- current use of oral anticoagulants
- Positive pregnancy test (beta-human chorionic gonadotrophin) for females
- intercurrent infections
- patients with prior gastric operations
Key Trial Info
Start Date :
January 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT00765596
Start Date
January 1 2005
Last Update
November 17 2011
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232