Status:
ENROLLING_BY_INVITATION
Analysis of HIV-1 Replication During Antiretroviral Therapy
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
HIV
Eligibility:
All Genders
18-99 years
Brief Summary
This study will determine if the level of virus in HIV-infected patients taking antiretroviral medications for prolonged periods decreases or persists at a stable level. It will also examine whether n...
Detailed Description
Combination antiretroviral therapy for human immunodeficiency virus serotype 1 (HIV-1) infection has resulted in profound reductions in viremia and is associated with marked improvements in morbidity ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Inclusion criteria for this protocol comprise all of the following conditions:
- Age greater than or equal to 18 years.
- HIV infection with documented reactive ELISA and positive western blot.
- Prior enrollment in 00-I-0110, 97-I-0082 OR patients with long term evaluation at NIH for whom additional sampling will be useful for protocol objectives, including:
- Available stored specimens from pretherapy period.
- Ongoing suppression of viremia with bDNA less than 50 copies/mL, OR
- Suppression of viremia to less than 50 copies/mL followed by rebound viremia during therapy.
- Patients must have a private physician for routine medical care.
- EXCLUSION CRITERIA:
- Any prospective study subject who has been previously withdrawn from any prior study for inability to comply with study procedures will be considered ineligible for this study.
Exclusion
Key Trial Info
Start Date :
November 17 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT00767312
Start Date
November 17 2008
Last Update
September 24 2025
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892