Status:
COMPLETED
Effect of Race/Ethnicity and Genes on Acetaminophen Pharmacokinetics
Lead Sponsor:
Tufts University
Collaborating Sponsors:
National Institute of General Medical Sciences (NIGMS)
Conditions:
Pain
Fever
Eligibility:
All Genders
18-64 years
Phase:
PHASE4
Brief Summary
Although acetaminophen is the most commonly used nonprescription drug in the USA, little is known regarding the influence of genes and race/ethnicity on acetaminophen disposition. The investigators lo...
Eligibility Criteria
Inclusion
- self-declared white/Caucasian
- self-declared African-American
- active
- ambulatory
- no evidence of medical disease
Exclusion
- alcohol use of 3 or more drinks per day
- HIV or hepatitis (B or C) infection
- isoniazid
- disulfiram
- phenobarbital
- phenytoin
- carbamazepine
- rifampicin
- valproic acid
- probenecid
- St. John's Wort
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT00768716
Start Date
December 1 2008
End Date
December 1 2013
Last Update
May 23 2019
Active Locations (1)
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1
Tufts Clinical Pharmacology Study Unit
Boston, Massachusetts, United States, 02111