Status:

COMPLETED

Conditioning Regimen Before Infusion of Allogeneic Hematopoietic Stem Cells

Lead Sponsor:

Cooperative Study Group A for Hematology

Conditions:

HEMATOLOGIC MALIGNANCIES

Eligibility:

All Genders

15-55 years

Brief Summary

Unrelated Donor Hematopoietic Stem Cell Transplantation After Nonmyeloablative Conditioning for Younger Patients with Hematologic Malignancies.

Detailed Description

Primary end points are treatment-related mortality and engraftment. Secondary end points are regimen-related toxicities, graft-versus-host-disease, relapse, and overall survival.

Eligibility Criteria

Inclusion

  • Patients should have an unrelated donor who is matched for HLA-A and -B by serology and for -DRB1 by molecular typing.

Exclusion

  • Patients should not have major illness or organ failure
  • Patients must not have a psychiatric disorder or mental deficiency severe as to make compliance with the treatment unlike, and making informed consent impossible.
  • Patients must not be pregnant or lactating.

Key Trial Info

Start Date :

December 1 2003

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT00770523

Start Date

December 1 2003

End Date

December 1 2008

Last Update

June 10 2011

Active Locations (1)

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1

Asan Medical Center

Seoul, South Korea, 138-736