Status:
COMPLETED
Airway Reactivity in Children Before and After BMT Bone Marrow Transplantation
Lead Sponsor:
Rambam Health Care Campus
Conditions:
Cancer
Eligibility:
All Genders
4-20 years
Brief Summary
Background: Stem cell transplantation (SCT) is associated with pulmonary complications and may lead to high morbidity and mortality. We encountered several children post-SCT with a clinical picture su...
Detailed Description
We encountered several children post SCT with clinical picture suggestive of airway hyper-reactivity (AHR) by spirometric evidence of reversible airway obstruction that was not reported pre transplant...
Eligibility Criteria
Inclusion
- age 4.5-20 years
- ability to perform spirometry consistently
- FEV1\>70% predicted
Exclusion
- FEV1\<70%
- inability to perform methacholine challenge test before and after stem cell transplantation.
Key Trial Info
Start Date :
July 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2007
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT00771836
Start Date
July 1 2004
End Date
July 1 2007
Last Update
October 15 2008
Active Locations (1)
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1
Pediatric Pulmonary Unit, Meyer Children's Hospital of Haifa, Meyer Children's Hospital, Rambam Medical Center, and the Bruce Rappaport Faculty of Medicine
Haifa, Israel