Status:

COMPLETED

Chronic Pain Management After Herniorraphy

Lead Sponsor:

Erasmus Medical Center

Conditions:

Chronic Pain

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Nowadays, chronic pain mainly as a result of iatrogenic nerve damage is generally considered as the most frequent complication after inguinal hernia surgery. The primary objective of this randomised d...

Eligibility Criteria

Inclusion

  • History of unilateral inguinal herniotomy
  • Establishment of neuropathic character of chronic pain by means the LANSS painscore and DN4 score
  • Abnormal sensitivity (allodynia, dysesthesia, hypoesthesia or dysesthesia) in or around the incisional area
  • Duration pain ≥ 3 months
  • Medial or lateral inguinal hernia
  • Age ≥ 18 years
  • VAS score ≥ 40 mm on Vas scale on which they indicate 'how unpleasant or disturbing the worst pain was that they had today'
  • Grade III or IV pain and discomfort on the 4-point pain and discomfort scale
  • Informed consent (addendum V)

Exclusion

  • Participation in another trial
  • Age \< 18 years
  • Cognitive disfunction
  • Patient is unable to speak Dutch
  • Hereditary problems of galactose intolerance, Lapp lactase deficiency or glucosegalactose malabsorption
  • Patient classified as American Society of Anaesthesiologist Class 4
  • Renal impairment

Key Trial Info

Start Date :

May 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2010

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT00772291

Start Date

May 1 2007

End Date

October 1 2010

Last Update

August 19 2011

Active Locations (1)

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1

Erasmus Medical Center

Rotterdam, Netherlands, 3015CE