Status:

COMPLETED

Vascular Improvement With Olmesartan Medoxomil Study

Lead Sponsor:

Daiichi Sankyo

Conditions:

Hypertension

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare in patients with primary hypertension, the non-blood pressure lowering effects of one-year therapy with olmesartan medoxomil vs. those of atenolol on changes in...

Eligibility Criteria

Inclusion

  • Male or female
  • 18-75 years of age
  • Mean seated diastolic BP 90-109 or mean seated systolic BP of 140-179

Exclusion

  • Secondary hypertension
  • Renal disease
  • Diabetes mellitus
  • Serum creatinine \>3.0 mg/dL
  • Hemoglobin \<10 mg/dL (males) or \<9mg/dL (females)
  • WBC count \<2000 cells/mL
  • Platelet count \<100,000 cells/mL
  • Either ALT \& AST \>2.5 x upper limit of normal
  • BMI \>35 kg/m2
  • TIA or cerebrovascular attack within 3 months of study entry

Key Trial Info

Start Date :

November 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2005

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00772499

Start Date

November 1 2002

End Date

July 1 2005

Last Update

October 15 2008

Active Locations (1)

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1

Wake Forest University Baptist Medical Center

Winston-Salem, North Carolina, United States, 27157