Status:
UNKNOWN
MOR and COMT SNP Polymorphism and Pain
Lead Sponsor:
East Tallinn Central Hospital
Conditions:
Pain Relief
Eligibility:
All Genders
18-75 years
Brief Summary
Patients with certain polymorphism in the MOR and COMT genes will display differences in their response to analgesics.
Detailed Description
After tissue injury, there is great interindividual variability among patients in the amount of pain experienced (pain intensity and duration of pain) and in the degree of pain relief from analgesics....
Eligibility Criteria
Inclusion
- 18 years of age and older
- Give informed consent to participate in this study
Exclusion
- Neurologic or psychiatric disease sufficient, in the clinical judgment of the investigator, to compromise informed consent or data collection
- ASA classification score 3 or above
- Patients with past or present history of substance abuse.
- Patients with a history of chronic pain requiring daily analgesic use for more then one month.
- Patients with a current diagnosis of anxiety or depression requiring medical treatment
- Patients allergic to morphine
Key Trial Info
Start Date :
October 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00773760
Start Date
October 1 2008
End Date
December 1 2009
Last Update
August 6 2009
Active Locations (1)
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1
Yuri Kolesnikov MD PhD
Tallinn, Estonia, 11312