Status:

COMPLETED

A Study of Monthly Subcutaneous Continuous Erythropoietin Receptor Activator (CERA) in Predialysis Participants With Chronic Renal Anemia

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Anemia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This single arm study will assess the long term maintenance of hemoglobin (Hb) levels, safety and tolerability of once monthly subcutaneous methoxy polyethylene glycol-epoetin beta (CERA) in predialys...

Eligibility Criteria

Inclusion

  • Chronic renal anemia;
  • Continuous subcutaneous maintenance darbopoetin alfa treatment during previous month;
  • Hb concentration between 10 and 12 g/dL;
  • Adequate iron status.

Exclusion

  • Transfusion of red blood cells during previous 2 months;
  • Significant acute or chronic bleeding, such as overt gastrointestinal bleeding;
  • Poorly controlled hypertension requiring hospitalization or interruption of darbopoetin alfa treatment in the previous 6 months;
  • Active malignant disease.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2010

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT00773968

Start Date

September 1 2008

End Date

March 1 2010

Last Update

April 4 2016

Active Locations (34)

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Page 1 of 9 (34 locations)

1

Barletta, Apulia, Italy, 70051

2

Molfetta (Ba), Apulia, Italy, 70056

3

Putignano, Apulia, Italy, 70017

4

Caserta, Campania, Italy, 81100