Status:

COMPLETED

Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations

Lead Sponsor:

Temple University

Collaborating Sponsors:

Pennsylvania Department of Health

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

40-80 years

Brief Summary

The overall purpose of PA-SCOPE is to determine why black and rural residents of Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations for chronic obstructive pulm...

Detailed Description

* Overall objective: To determine why African American and rural residents of Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations for COPD-and to show that repea...

Eligibility Criteria

Inclusion

  • Phase 1 \& Gene Expression: --Current hospitalization for COPD exacerbation
  • Phase 1 \& 2: COPD \& ONE of the following criteria:
  • History of hospitalization for COPD exacerbation, OR
  • Currently on supplemental oxygen, OR
  • History of evaluation for lung transplant or LVRS, OR
  • \>/= 6 months post-LVRS
  • Phase 1 or 2:
  • Current or former smoker, \>/= 20 pack-yr. smoking history
  • FEV1 \</= 70%; FEV1/FVC \</= 70%
  • Life expectancy of \> 6 months

Exclusion

  • \< 20 pack-yr. smoking history
  • Diagnosis of pulmonary fibrosis, bronchiectasis, mediastinal mass, or presence of a pulmonary mass
  • Asthma
  • FEV1 \> 70% or FEV1/FVC \>70%

Key Trial Info

Start Date :

June 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

1066 Patients enrolled

Trial Details

Trial ID

NCT00774176

Start Date

June 1 2004

End Date

May 1 2008

Last Update

June 29 2017

Active Locations (3)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (3 locations)

1

Lancaster General Hospital

Lancaster, Pennsylvania, United States, 17604

2

Temple University School of Medicine

Philadelphia, Pennsylvania, United States, 19140

3

Western Pennsylvania Hospital

Pittsburgh, Pennsylvania, United States, 15224