Status:
COMPLETED
Combustion Derived Air Pollution and Vascular Function
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
National Institute for Public Health and the Environment (RIVM)
Conditions:
Endothelial Dysfunction
Eligibility:
All Genders
Phase:
NA
Brief Summary
Air pollution is a major cause of cardiovascular morbidity and mortality. The components of air pollution responsible and the mechanisms through which they might mediate these harmful effects remain o...
Eligibility Criteria
Inclusion
- Healthy volunteers
Exclusion
- Current smokers
- Significant occupational exposure to air pollution
- History of lung disease
- Women of child-bearing potential
- Malignant arrhythmias
- Renal or hepatic failure
- Significant co-morbidity
- Systolic blood pressure \>190 or \<100 mmHg
- Previous history of blood dyscrasia
- Unable to tolerate the supine position
- Lack of informed consent
- Blood donation within last 3 months
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2006
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00775099
Start Date
September 1 2005
End Date
March 1 2006
Last Update
October 17 2008
Active Locations (1)
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1
University of Edinburgh
Edinburgh, United Kingdom, EH16 4SB